Vanilla: Female and male Charr are equal and are all soldiers. In the Sylvari storyline and the dungeon storyline, there is a subplot about one of the party members, Caithe, being in a relationship with a villainess Faolain, though you can easily miss it if you don't play Sylvari or do the dungeons.
Season 1 dumps the original Destiny's Edge group because GW2's launch was fumbled and they were trying to cut expenses, and Destiny's Edge had top voice actors like Steve Blum, Matthew Mercer, Kari Wahlgreen, etc. So a new cast gets brought in (before the old one got brought back in HoT because we can afford Steve Blum and co now). Braham is Eir's inexplicable black son, even though Norn are all white and no black tribe is ever mentioned. Not quite woke, but Taimi has an annoying California college valley girl personality and has a frustrating mary sue moment in season 2. Marjory and Kasmeer have a minor lesbian subplot, but it only comes up a few times in season 2 and then rarely throughout the rest of the game.
Hardly anything from HoT through season 4.
Icebrood Saga: it turns out that Rytlock had a son we had never heard of before, to which he was an absentee dad (though that is the norm for Charr culture). Rytlock - despite being a high ranking Tribune of the Blood Legion and having been the Charr Legion's representative in the successful campaigns against three Elder Dragons (3/6 now dead), refuses to take up a leadership role within the Charr legions, and instead avoids authority. The narrative is about guilting how bad of a dad he was an ends with him killing his son when he leaps at his mate. His mate (new character introduced in IBS) then succeeds Imperator Ruinbringer as the leader of the Blood Legion, and then becomes representative of all of the Charr legions in the Tyrian Alliance. By this point, all of the racial leaders are women. One of the two main villains, Jormag, was originally described as being male in Vanilla, but retconned into being female (actually referred to as a "they" a couple of times, though it can be easily overlooked), which I thought was a good choice in differentiating the Elder Dragon cast.
End of Dragons: this is when it became insufferable, because this is by far the longest GW2 story yet clocking in at 11 hours in length, but the only exciting adventure stuff happens at the beginning with the airship setpiece, and at the end when you fight Soo-Won and then the Dragonvoid. The 8 hours in between is almost entirely standing around listening to pathetic pirate melodrama, or doing dull stuff like waiting at the DMV, or fixing people's air conditioners, or rummaging through people's apartments for clues. We get cutscenes about women standing around talking about their feelings (and some really cringeworthy dialogue). There is a subplot about how the general of the Canthan empire is bad because he doesn't trust the empress or Joon (the engineer and megacorp CEO working with the Elder Dragon Soo-won), even though it is his responsibility to protect the people of Cantha and the empress and Joon do not have a handle on the situation. There is an infamous mandatory quest where you have to "beat the bigot", and your character has a voiced line about that.
EoD patches: one of the main party members, Yao, calls himself "your local friendly agender engineer". That's about it.
I didn't play past EoD because the GW2 storyline was finished, and the game was holistically declining in quality, not just the story. Map design and art was declining, lack of new enemy models, the new EoD elite specs shipped in a broken and lackluster state, no new PvP or WvW maps, etc. The music got better, though, but that wasn't enough.